Signals · Trials in flight
Vendors make claims; trials test them. This is the public registry of studies of ambient AI documentation, LLM-assisted notes, and EHR-burden interventions — pulled at build time from ClinicalTrials.gov.
Recruiting
Started 2026-05-05 · n=250
University of Wisconsin, Madison · other
The goal of this clinical trial is to learn whether using Ambient Artificial Intelligence for nursing staff documentation in an inpatient setting will reduce the time spent in flowsheet documentation and enhance nurse staffing wellbeing. Participants will use Ambient Listening AI
Recruiting
Started 2025-12-15 · n=90
University of Pennsylvania · other
Inpatient general medicine attendings will be randomized to have an LLM feature turned on to provide a draft of an off-service handoff within Carelign (an EHR-adjacent provider communication tool). Providers who have access to this feature will be clearly instructed that if they
Recruiting
Started 2025-07-01 · n=17,800
Swedish Medical Center · other
Prospective, multi-center, cluster-randomized trial of a hospital Infection Preventionist (IP)-led quality improvement study to provide clinical teams with just-in-time clinical education and reinforcement of existing best practices recommendations based on the output of a possib
Recruiting
Started 2025-01-05 · n=300
Pedro Angelo Basei de Paula · other
The goal of this randomized clinical trial is to learn whether an "ambient AI scribe" (Voa Health) can reduce documentation burden and improve physician well-being and patient experience in outpatient clinics. The AI scribe listens to the audio of the consultation and produces a
Active · not recruiting
Started 2025-11-26 · n=80
Kirsehir Ahi Evran Universitesi · other
This randomized, four-arm clinical trial will investigate the effects of large language model (LLM)-assisted exercise prescriptions integrated with conventional physiotherapy on pain, function and quality of life in adults with degenerative knee disease. Participants will be rand
Active · not recruiting
Started 2025-09-15 · n=60
Dana-Farber Cancer Institute · other
The goal of this study is to test the accuracy of Large Language Model-generated serious illness communication (SIC) summaries, the feasibility of delivering the SIC summaries, and to collect perspectives on the SIC summaries from clinicians and participants with cancer. Large La
Active · not recruiting
Started 2025-04-14 · n=105
Children's Healthcare of Atlanta · other
The goal of this rapid, randomized quality improvement trial is to learn if implementing generative AI scribe software can enhance physician documentation efficiency and reduce burnout in outpatient providers at Children's Healthcare of Atlanta facilities. The main questions it a
Active · not recruiting
Started 2021-06-21 · n=456
Tufts Medical Center · other
The overall objective of this study is to reduce the burden of chronic kidney disease (CKD) and its consequences for an aging U.S. population. To accomplish this, the investigators propose to conduct a multi-center randomized trial of an advance care planning (ACP) video interven
Active · not recruiting
Started 2000-01-01 · n=20,000
Rambam Health Care Campus · other
This study will evaluate the performance of a large language model (LLM)-based clinical decision support system in the emergency department at Rambam Health Care Campus. The system analyzes structured patient data from the electronic health record and generates diagnostic and tre
Not yet recruiting
Started 2026-06-01 · n=786
Pavol Jozef Safarik University · other
Background: Physicians worldwide face an increasing administrative burden that diverts time from direct patient care. Among inpatient documentation tasks, authoring hospital course summaries is particularly time-consuming and critical for safe care transitions. Large language mod
Not yet recruiting
Started 2026-02-28 · n=10
China National Center for Cardiovascular Diseases · other_gov
This study develops and validates a privacy-preserving OCR-LLM pipeline that converts admission history of present illness (HPI) records into structured coronary syndrome subtypes (STEMI, NSTEMI, unstable angina, and chronic coronary syndrome). The system first extracts text from
Not yet recruiting
Started 2026-01-01 · n=1,000
MetroWest Artificial Intelligence Research Workgroup · other
This is a prospective, unmasked, randomized, multicenter clinical trial evaluating the impact of point-of-care large language model (LLM)-based decision support on diagnostic accuracy and clinical outcomes in adult medical intensive care unit (MICU) patients. Consecutive adult IC
Not yet recruiting
Started 2025-09-01 · n=1,092
Julian Schwarz · other
This study investigates the feasibility and impact of patient access to clinical notes written by their healthcare providers-a concept known as Open Notes. While international research has already demonstrated positive effects of Open Notes on patient empowerment and treatment ou
Not yet recruiting
Started 2025-08 · n=64
University of Saskatchewan · other
The goal of this clinical trial is to assess the impacts of ambient AI scribes on the workload and burnout in physicians who see patients in a clinic setting at least twice in a week, as well as the impacts on patient-physician interaction. The main questions it aims to answer ar
Completed
Started 2025-06-18 · n=200
University of Saskatchewan · other
This randomized study compares AI-generated clinical documentation with traditional dictation templates during orthopedic consultations. Patients are randomized to have their consultation documented using either an AI medical scribe or a routine dictation template. Outcomes inclu
Completed
Started 2025-02-18 · n=21
Kyoto University, Graduate School of Medicine · other
The goal of this clinical trial is to learn whether an LLM-assisted writing workflow can reduce the time to complete hospital discharge summaries and discharge referrals and maintain or improve document quality compared with writing from scratch by clinicians. The study used six
Sorted by status (recruiting first), then by start date. Updated at build · 2026-05-15.